Effect of Priming Dose of Atracurium on the Onset of Muscle Relaxation: A Controlled Clinical Trial

ABSTRACT The aim of this study was comparison of priming and intubating dose of Atracurium on the onset of muscle relaxation time to testing an alternative method for urgent operation. one hundred, 20-30 years old men that were condidate for urgency surgery entered in this study and divided in two groups randomly. First group was relaxed with Priming dose of Atracurium. In this way, %5 mg (priming dose) and 0.8 mg/kg 2 muinute Later and Second group was relaxed with 0.5 mg/kg Atracurium (intubating dose). The time of onset for relaxation measured by Trian-of-four mode by nerve Stimulator. Mean of this times compared using t-Student test. The onset of relaxation was earlier with use of Priming dose 70±10 Second) in compairsion to intubaiting dose (300±31 Seeond) The priming dose of Atracurium could decrease the time for onset of intubating time.